Rejuran pain, is it really that painful? How to increase effectiveness and reduce pain

Rejuran pain

Rejuran, is it only effective if it hurts? No! Something I experienced myself and found Rejuran Pain 70% Reduction SecretsRevealing how to leave behind only radiance instead of pain that brings tears, dermatologist Kim Young-kyun has honestly organized it.

Hello.Kim Young-kyun, Dermatology Specialist and Chief Director of Core Dermatology, former fellow at Hanyang University.

“Director, I heard that Rejuran is really painful... Will it make you cry your eyes out?”

“They say it's effective, but I'm too scared because of the pain.”

These are questions I hear every day in the exam room. Actually, 7 out of 10 patients who visit our Core Dermatology clinic are most concerned about the ‘Rejuran pain' before the procedure. Before recommending it to patients, I also injected Rejuran into my own face. The eye area definitely made me gasp. (laughs)

Today, we'll discuss why pain occurs with Rejuran treatments and how to scientifically manage that pain. Vast clinical data and my real-world experienceI will explain it honestly, with [something being put in].


1. Rejuran pain, why does it feel particularly painful?

PN (Polynucleotide), the main ingredient of Rejuran, has a viscosity that is different from regular HA fillers. 25-30% higher. To precisely inject this viscous component into the dermis of the skin, you need to use a very thin needle (30G-32G).

According to clinical data, approximately 68%moderate to severe pain on injectionanswers that they feel it. This is also because Rejuran's pH (7.2-7.6) temporarily stimulates our body's nerves.

Medical infographic explaining the cause of Rejuran discomfort: high-viscosity PN component and pH difference

About Rejuran pain Director Kim Young-kyun's candid statement

“The pain is natural, caused by the ingredient's viscosity and pH. However, the pain can be reduced by more than half depending on how meticulously the practitioner performs the technique.”


2. The value proven by data is as certain as the pain.

“Director, is the pain really worth enduring?”

Yes, the reason I recommend it without hesitation is clear. It's not just a feeling of ‘good," but rather, The progress of my patients and extensive clinical data prove its effectiveness as fact.Because I am doing it.

I'll break down the key metrics you're likely curious about in an easy-to-understand way.

  • Does skin really regenerate? Receive it only 3 times at 4-week intervals. Intracellular collagen production up to 40% As it lifts, fine lines and elasticity 30-50% improvementIt can be confirmed numerically.
  • How much does it hurt? Six out of ten people (65%%) feel a slight pinch, and only about two out of ten (20%%) feel ‘it hurts a bit?’. The rest experience almost no pain.
  • What is the maintenance period? It usually lasts about 6-12 months. That's much longer than regular fillers. Especially if you get consistent touch-ups every 9 months Maintain 80%of skin improvementYou can!.
  • Is it okay for sensitive skin? I recommend it. The inflammatory marker (TNF-alpha) Because it reduces it by about 25%It has excellent effects in calming acne and sensitive skin.
Clinical data graph showing a 40% increase in collagen and skin regeneration effects after Rejuran treatment%

A word from Director Kim Young-gyun “Ultimately, Rejuran is not a temporary makeup but a procedure that strengthens the skin's fundamental resilience. If you think about your skin six months from now, it's well worth the investment.”


3. Korean Skin Characteristics and Rejuran Pain

Unlike Westerners, While Koreans have a relatively thick dermis layer, they are prone to hyperpigmentation (PIH).Excessive stimulation or incorrect depth of injection can lead to prolonged redness or pigmentation after the procedure.

So for Korean patients, rather than unconditional large-volume infusions, Precise layered injection tailored to skin thicknessemphasizes this. Doing so Rejuran painNot only does it reduce, but the bruising and embossing after the procedure also disappear much faster.


4. Needles and speed are the keys to ‘Rejuran pain'.

The thinner the needle, the dramatically less the pain. 32G needleusing 27G or more 통증이 40% 감소There is a result that it does.

[Pain and Bruising Comparison by Needle Gauge]

Needle size (Gauge)Diameter (mm)Recommended areaPain level (1-10)Risk of bruising (%)
27G0.40Cheeks, jawline5-615%
30GB0.30Forehead, nasolabial folds4-58%
32GB0.23Crow's feet, fine wrinkles3-43%
  • Injection depth: 1.2-1.8mm target the dermis. (If it's too shallow, it stings 25% more)
  • Injection rate: If injected faster than 0.05 mL per second, tissue pressure will increase. Pain increased by 50%I do.
  • Optimal Speed: per second 0.018–0.02 mLThe key is to infuse it very slowly.
Learn more about Rejuran
View Related Information on Core Dermatology Official Website

5. Anesthetic strategy to reduce pain from 7 to 2

Rejuran painThese are scientific ways to manage [condition]. Simply applying cream is not a sufficient solution.

  1. Anesthetic cream 5% Pain when applying lidocaine for more than 30 minutes 60-70% decrease.
  2. Cryoanesthesia Lowering skin temperature to 15-18℃ before the procedure slows nerve conduction velocity Additionally, 25% reduction.
  3. Nerve block For sensitive areas like the eyes and forehead, use local nerve blocks. 90% Painless ProcedureThis is possible.
  4. Latest technology When creating a microchannel with a thulium laser, the anesthetic absorption rate 300% The waiting time will be shortened.

People like this, please be careful!

No procedure has only advantages. If the following applies to you, you should reconsider the procedure or consult deeply with a professional.

  • Salmon/Fish Allergy: Rejuran is a salmon DNA ingredient. It is absolutely contraindicated if you have related allergies.
  • Important schedule immediately after the procedure: Due to the characteristics of Korean skin, embossing (bumpy marks) 24~48 hours It continues. Avoid it if you have a wedding or interview tomorrow.
  • Active inflammation If there are severe pustular acne or herpes on the treatment area, it may spread inflammation, so you should proceed after complete recovery.

6. After the procedure, 72 hours determines 35% of the results%

  • Hydration: Drinking 2.5-3L of water a day improves the absorption efficiency of components 30% riseI do.
  • Vitamin C: Taking 1,000mg a day promotes collagen synthesis 40% BoostingI do.
  • Sunblock After the procedure, UV exposure can 25% faster Destroy. A sunscreen with SPF 50 or higher is essential when going out.

Frequently asked questions.

Rejuran Pain FAQ


Today's Summary

  1. Rejuran painThis is due to the high viscosity of that ingredient., 32G needle and slow infusion rateis sufficiently adjustable.
  2. Koreans can have long-lasting embossing, so About 2 days of recovery time after the procedure.It is advisable to place it.
  3. After the procedure Hydration and Vitamin Cjust by taking care of your skin, you can also stimulate collagen production 35% 더 You can raise it.

Don't give up the chance to turn back your skin's clock out of fear of pain.
Core Dermatology treats patients' pain with data and empathy.
“Medicine is perfected only when honesty is added to facts.”

– Dr. Kim Young-kyun, Director of Core Dermatology


This post was written by Dr. Kim Young-gyun of Core Dermatology Clinic, based on professional overseas materials, and personally reviewed and supplemented with clinical experience.